Health economics and compliance of vials/syringes versus pen devices: a review of the evidence
The use of pen devices improves the health economics benefits and adherence to insulin therapy.
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Analysis of Symposium Articles on Insulin Pen Devices and Alternative Insulin Delivery Methods
Although these administration methods, especially insulin pens, have some clear advantages over the vial/syringe, there are also limitations to their use and careful patient selection and education are still needed.
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Evolution of Diabetes Insulin Delivery Devices
The low rate of insulin pen usage in the United States compared with European countries and the fact that many patients report that they are not offered the option of an insulin pen by their physician suggest that there is a need to increase patient and provider awareness of the currently available devices for insulin administration.
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Medication 
