Diabetes PubMed

These experiments suggest that the primary effect of glyburide on the beta cell is to increase its responsiveness to glucose.

C-reactive protein (CRP) in the glyburide and metformin groups was positively associated with changes in weight, but this was not the case with rosiglitazone.

Unless future studies refute current data regarding the efficacy and safety of glyburide, we believe that, owing to its ease of administration, convenience and low cost, glyburide will become the first line of medical treatment in patients with gestational diabetes mellitus within the next few years.