Helal I, Goucha R, Karoui C, Abderrahim E, Hamida FB, Elyounsi F, Maiz HB, Abdallah TB, Kheder A.
Department of Internal Medicine A and Laboratory of Kidney Pathology 02, Charles Nicolle Hospital Boulevard 9 Avril. 1006 Tunis Tunisia.
INTRODUCTION: Diabetic nephropathy can occur during the course of both type1 and type 2 diabetes mellitus. The characteristic lesions are diffuse or nodular (Kimmelsteil-Wilson) diabetic glomerulosclerosis. The reported cases represent unusual presentations of diabetes mellitus. CASE PRESENTATION: We report the case of a 49-year-old man without prior history of diabetes mellitus who presented with rapidly progressive renal failure and whose renal biopsy revealed nodular (Kimmelsteil-Wilson) glomerulosclerosis lesions characteristic of diabetes. CONCLUSION: Renal manifestations of diabetes mellitus may antedate other more common presenting symptoms of this disease and we critically review the literature on this subject.
PMID: 19918545
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